Table 2.

Etiology of extreme thrombocytosis^∗

Causes	Percentage reported
Infection	31%
Postsplenectomy	19%
Malignancy	14%
Trauma	14%
Inflammation	9%
Blood loss	6%
Rebound thrombocytosis	3%
Uncertain etiology	4%

∗Adapted from Buss DH et al, 1994 (1) with permission from Elsevier. Extreme thrombocytosis is defined as a platelet count ≥1000 K/μL (15).