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Pharmacologic agents for management of extreme thrombocytosis and associated adverse effects∗
| Drugs | Adverse effects |
| Acetyl salicylic acid | Bleeding |
| Hydroxyurea | Venous thrombosis, leukemic transformation |
| Anagrelide | Anemia, headache, tachycardia, edema |
| Interferon alpha | Immunosuppression |
| Ticlopidine | Bleeding, leukemic transformation |
| Enoxaparen | Bleeding, thrombocytopenia, headache |
| Plasmapheresis | Bleeding, infection, lung injury |
