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Interaction of AR and MCM7 leading to increase of chromatin association of MCM6, Cdt1, and geminin. PC3+AR or PC3+ΔAR cells were treated with R1881 at 0, 0.01, and 10 nmol/L. Chromatin from these cells was purified. The chromatin-associated proteins were analyzed in immunoblots using antibodies specific for MCM7, MCM6, geminin, and Cdt1. Antibodies against histone 3 were used as normalization controls.
