Figure 2.

Induction of apoptosis after UV exposure in MPNST cells. MPNST cells with high- and low-Ras signaling activity were exposed to UV (10 mJ/cm²) and the induction of apoptosis was measured after 6 hours using the Annexin-V conversion test. A: The average (±SD) percentage of apoptosis occurring after UV exposure is plotted for two groups including high-Ras (6IE4 and 37-3-18) and low-Ras MPNST cells (35-1-2, 38-2-18, and 35-5-24-12). B: Annexin-V labeling results obtained for 37-3-18 and 38-2-18 cells after exposure to UV. The top right quadrant represents cells committed to undergoing apoptosis.