Table 3.
Sema3E Expression in Melanocytic Cells in Benign Naevi, Primary Cutaneous Melanomas, and Melanoma Metastases
| % Positive melanocytic cells | Naevi naevocellularis | Dysplastic naevi | Melanomas in situ | Primary melanomas
|
Melanoma metastases
|
||||
|---|---|---|---|---|---|---|---|---|---|
| Clark II | Clark III | Clark IV | Skin | Lymph node | Brain | ||||
| 0 | 2 | 1 | 1 | 1 | 1 | 2 | 5 | 2 | |
| 1–25 | 1 | 2 | 2 | 1 | |||||
| 26–50 | 1 | 1 | 1 | ||||||
| 51–75 | |||||||||
| 76–99 | 1 | 1 | |||||||
| 100 | 8 | 3 | 4 | 3 | 3 | 3 | |||
| N+/Nt* | 9/11 | 3/4 | 4/4 | 5/6 | 3/4 | 6/7 | 2/4 | 2/7 | 1/3 |
| % | 82% | 75% | 100% | 83% | 75% | 86% | 50% | 29% | 33% |
*
Number of Sema3E positive lesions (N+) per total number of examined lesions (Nt).