Skip to main content
. Author manuscript; available in PMC: 2009 Jan 14.
Published in final edited form as: Cell. 2008 Jul 11;134(1):97–111. doi: 10.1016/j.cell.2008.04.052

Figure 5. Regulation of LXR signaling by SULT2b1 during T cell activation.

Figure 5

(A) Real-time PCR analysis of LXRβ and ABCG1 from quiescent WT T cells cultured with simvastatin and 5 mM mevalonic acid. (B) Real-time PCR analysis of SULT2b1, ABCC1, LDLR and ABCG1 mRNA from purified WT T cells stimulated with anti-CD3 in vitro for the indicated times. (C) Real-time PCR analysis of SULT2b1 and ABCG1 mRNA from purified WT T cells stimulated for 12 h with anti-CD3 in vivo. (D) Real-time PCR analysis of LXRβ, LDLR and ABCA1 mRNA from CAR-tg T cells transduced with SULT2b1- containing or control Adenovirus.