Table 2.
Effect of DPP treatment on incidence of diabetes
| Placebo
|
Metformin
|
ILS
|
||||
|---|---|---|---|---|---|---|
| GDM (n = 122) | No GDM (n = 487) | GDM (n = 111) | No GDM (n = 464) | GDM (n = 117) | No GDM (n = 465) | |
| Incidence of diabetes (number of cases per 100 person-years)a | 15.2b | 8.9 | 7.8 | 7.8 | 7.4 | 4.7 |
| Reduction in incidence (compared with placebo)a | 50.4c | 14.4 | 53.4c | 49.2c | ||
| Number needed to treat (to prevent one case in 3 yr compared with placebo)a | 6.1 | 24.0 | 5.3 | 9.0 | ||
a
Adjusted for age.
b
P < 0.05 compared with non-GDM group.
c
P < 0.05 compared with placebo.