FIG. 6.

Surfactant accumulation in mice lacking ERβ. (A) Histology of lungs from 1-year-old WT and ERβ^−/− female mice. Lungs obtained from WT and ERβ^−/− mice were fixed by immersion, sectioned, and stained with hematoxylin-eosin. (B) Immunostaining for SP-A and proSP-C in 1-year-old WT and ERβ^−/− female mouse lungs. Lungs obtained from WT and ERβ^−/− female mice were fixed, and serial sections were stained with antibodies for SP-A and proSP-C. Counterstaining was done with hematoxylin.