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. 2009 Jan 15;20(2):631–641. doi: 10.1091/mbc.E08-01-0099

Figure 2.

Figure 2.

ACS-mediated silencing effects in ARS1 and core X. ARS1-URA-tel, GF6, GF44, ARS1(ACS−)-URA3-tel, GF6(ACS−), GF44(ACS−) (diagrams shown on top) were inserted in the VII-L telomere of wild-type (MCM5, W303) and mutant (mcm5-461, orc2-1, orc5-1, cdc45-1, Δsas2, cdc7-1, cdc6-1, and Δsir2) strains, and %FOAR was determined for each construct/strain combination. Raw data are shown in Supplemental Table 2. (A) The ratio %FOAR(ACS−)/%FOARACS as indicated above each graph represents the effect of destruction of ACS in the construct shown on top in the strains shown on the left. In these exponential graphs, values below 1 depict derepression and values above 1 depict increased repression. (B) The ratio %FOARGF6(ACS-ΔSTAR)/%FOARGF6(ΔSTAR) shows the effect of destruction of ACS in the absence of STAR element.