Table 4.
All A | All B | All C | All D | All E | CP A | CP B | CP C | CP D | CP E | RAP A | RAP B | RAP C | RAP D | RAP E | |
GA | 95 (80.5) |
44 (81.5) |
201 (79.8) |
218 (76.2) |
71 (86.6) |
72 (81.8) |
37 (80.4) |
124 (77.8) |
140 (74.5) |
42 (87.5) |
23 (76.7) |
7 (87.5) |
77 (83.7) |
78 (80.0) |
29 (85.3) |
AT | 20 (17.0) |
9 (16.7) |
46 (18.3) |
52 (18.2) |
10 (12.2) |
13 (14.8) |
8 (17.4) |
32 (20) |
40 (21.3) |
5 (10.4) |
7 (23.3) |
1 (12.5) |
14 (15.2) |
12 (12.2) |
5 (14.7) |
Other | 3 (2.5) |
1 (1.9) |
5 (2.0) |
16 (5.6) |
1 (1.2) |
3 (3.4) |
1 (2.2) |
4 (2.5) |
8 (4.3) |
1 (2.1) |
0 (0) |
0 (0) |
1 (1.1) |
8 (8.2) |
0 (0) |
Fisher P-value | 0.47 | 0.68 | 0.16 | 0.10 | 0.73 | 0.87 | 0.51 | 0.08 | 0.02 | 0.66 | 0.19 | 1.0 | 0.87 | 0.87 | 1.0 |
Haplotype counts among the subject groups subdivided by the subject's response to the pain question (percentage of total haplotype count in parentheses). Haplotypes are formed by rs8007267 and rs3783641. AT was reported to be the "pain-protective haplotype" [7]. "All" is CP and RAP combined. Fisher's Exact Test compares each category with the haplotype frequencies in the overall control group.