Effect of Lnk on SCF-, bFGF-, and IL-6/sIL-6R-induced Elk-1 reporter activity. 293 cells were transfected with an Elk-1 reporter plasmid and the indicated amounts of Lnk plasmid. In the experiment with SCF, the c-Kit plasmid was also used. The cells were stimulated on the following day with either SCF (20 ng/ml), bFGF (1 ng/ml), or IL-6/sIL-6R (20 ng/ml) for 6 h, and luciferase activities in the cell lysates were measured.