Figure 2. A granuloma map used to assess the slides from patients with granumatous diseases.

This example represents the type of granuloma map used to assess the tissue biopsies of patients with pleural TB for the absence or presence of granulomas and type (necrotic or non-necrotic) of granuloma. Once the granuloma was identified, ISH was used to stain the tissue for mRNA cytokine expression. Magnification 25×.