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. Author manuscript; available in PMC: 2009 Oct 15.
Published in final edited form as: J Am Chem Soc. 2008 Sep 18;130(41):13709–13717. doi: 10.1021/ja804087r

Figure 6.

Figure 6

Plot of kobsd versus mole fraction of DME (XDME) for the rearrangement of 7e (0.004 M) by LDA (0.05 M) at -60 °C. The donor solvent concentration is held constant ([DME]+[n-BuOMe]=5.0 M) using pentane as cosolvent. The curve depicts an unweighted least-squares fit to kobsd = (a + bx)/(1 + cx) (a = (0.0 ± 0.1) × 10-3, b = 1.6 ± 0.5, c = 0.5 ± 0.4) such that 1 + c = Keq (see eq 16). At low DME concentrations the lithium phenolate precipitated during the reaction; the value of kobsd (shown as *) was not included in the fit.