TABLE 2.
The C-terminal tail of Rap1p is not essential for determination of replicative capacity of telomerase-deficient K. lactis, and RIF1 is not essential for determination of replicative capacity of telomerase-deficient S. cerevisiae
| Strain | Initial telomere length (bp) | Range of final telomere length (bp) | Δ shortening (bp) | Replicative capacity (no. of passages)
|
|
|---|---|---|---|---|---|
| Avga | Maximal | ||||
| RAP1 low copy | 495 | 190-215 | 320 | 2.01 ± 0.05 | 3 |
| rap1-ΔC low copy | 525 | 190-215 | 335 | 2.58 ± 0.18 | 4 |
| RAP1 high copy | 675 | 190-215 | 505 | 3 ± 0.18 | 4 |
| rap1-ΔC high copy | 1,325 | 210-340 | 1,110 | 4.79 ± 0.68 | 9 |
| RIF1 (S. cerevisiae) | 500 | 205-245 | 295 | 1.91 ± 0.13 | 3 |
| Δrif1 (S. cerevisiae) | 1,100 | 220-340 | 790 | 3.38 ± 0.27 | 5 |
a
Data are means ± standard deviations.