Fig. 5.

A comparison of tumor retention and renal embolization between the control and treated groups. Kidney sections from two animals from each group are scanned using the HP scanjet 7400c (magnified x 2). Group 1 is the control and it has the most tumor, as demonstrated by the blue/purple areas (see also Fig. 1) and this was confirmed histologically as being VX2 carcinoma. The tumor is diffusely spread throughout the kidney. Groups 2A, 2B and Group 3 have less VX2 carcinoma than the control group, and the tumor is still distributed throughout the renal parenchyma. Groups 4, 5, 6 and 7 are all similar to each other and they are very different from Groups 1, 2A, 2B and 3. However, Group 4 appears to have more blue/purple tumor than Groups 5, 6 and 7. The kidneys of these latter 4 groups are smaller and completely embolized. The remaining tumor is not diffusely distributed throughout the parenchyma, but it is generally at the capsular surface, in the attached peri-renal fat or in the pelvis of the kidney. The blue/purple is either tumor or inflammation or mineralization, and it frequently shows all three in the sections (see Fig. 6).