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Analysis of rearrangements among 7#7-7-6 sample subclones (day 64). Cellular DNA was codigested with BamHI and PstI and was probed as indicated in the legend to Fig. 2. The subclone DNA in lanes 3, 5, 6, 7, 8, and 14 exhibited intact transgenes as indicated by 3.4- and 2.4-kb bands. The remaining subclones were rearranged, as was the subclone in lane 4, as discovered upon a subsequent EcoRI analysis (data not shown) (see Materials and Methods).
