TABLE 2.

Suppression of adaptation defects caused by rad51Δ and other mutations

Strain description	% Adaptation ± SD at 24 h after galactose induction
Strains with epistatic relationships
rad51Δ	27.6 ± 4.9
rad51Δ srs2Δ	29.5 ± 3.5
rad51Δ tid1Δ	0.3 ± 0.1
srs2Δ tid1Δ	0.0 ± 0.0
srs2Δ rad52Δ	85.3 ± 3.6
rfa1-t11	95.1 ± 3.5
tid1Δ rfa1-t11	86.0 ± 8.4
rad51Δ rfa1-t11	64.0 ± 15.2
srs2Δ rfa1-t11	18.8 ± 7.6
rad51Δ tid1Δ rfa1-t11	28.0 ± 4.1
rad52Δ tid1Δ rfa1-t11	17.8 ± 9.9
rad51Δ rad52Δ tid1Δ	14.3 ± 12.1
rad52Δ rfa1-t11	25.0 ± 2.8
Strains with suppression by Rad51 mutants
rad51Δ pPGK::RAD51, 2μm	68.3 ± 8.3
rad51Δ pPGK::rad51-K191A, 2μm	71.9 ± 3.7
rad51Δ pPGK (empty vector) CEN ARS	25.7
rad51Δ pPGK::rad51-K191A CEN ARS	71.7
srs2Δ pPGK (empty vector) CEN ARS	20.8
srs2Δ pPGK::rad51-K191A CEN ARS	33.0
rad51Δ pPGK::rad51-K191R, 2μm	82.3 ± 2.1
rad51Δ pADH::rad51-L99P, 2μm	77.3 ± 10.3
rad51Δ pADH::rad51-S146A, 2μm	62.8 ± 6.1
rad51Δ pADH::rad51-Y388H, 2μm	27.9 ± 7.2