Change from baseline in MADRS Total score (last observation carried forward) in the two randomized, double-blind, placebo-controlled studies of adjunctive aripiprazole.
**p < 0.01 vs placebo.
***p < 0.001 vs placebo; MADRS Total score is rated from 0 to 60, where a negative change indicates improvement.
Abbreviations: MADRS, Montgomery – Asberg Depression Rating Scale; LOCF, last observation carried forward.