Table 2.
Summary of Pregnancy Outcomes, Fertility Rate and Flares Presented in Mean (%) ± SEM from Published Studies Compared to Our Present Case- Control Study Findings
| N | Literature Review |
Present Study-SLE Cases |
Present Study-Controls |
|
|---|---|---|---|---|
| Elective termination (%) |
44 | 10.5 ± 1.5 | 2.9 | 4.0 |
| Fetal wastage (%) | 45 | 19.5 ± 1.6 | 18.3 | 16.6 |
| Neonatal death (%) | 39 | 2.2 ± 0.4 | 1.7 | 0.4 |
| Preterm birth (%) | 43 | 25.5 ± 2.2 | 9.5 | 4.9 |
| Full term birth (%) | 44 | 49.0 ± 2.5 | 69.3 | 74.5 |
| Live birth (%) | 50 | 72.3 ± 1.9 | 78.8 | 79.4 |
| Pregnancy rate (mean) |
7 | 2.3 ± 0.08 | 2.3 ± 0.2 | 1.8 ± 0.1 |
| Flares during pregnancy (%) |
38 | 28.6 ± 2.6 | 18 | |
| Flare-up postpartum (%) |
24 | 11.9 ± 2.0 | ||
| Total flares (%) | 39 | 36.5 ± 3.3 | ||
| IUGR (%) | 20 | 14.8 ± 0.8 | ||
| Preg-induced HTN (%) |
17 | 15.9 ± 2.7 | 19.3* | 17.2* |
| Gestational DM (%) |
8 | 6.7 ± 1.6 | 7.2 | 5.4 |
| APL ab (%) | 13 | 36.8 ± 6.1 | ||
| Neonatal lupus (%) | 25 | 2.4 ± 0.6 |
Elective termination= termination for personal or medical reasons
Fetal wastage= sum of miscarriages or spontaneous abortions and stillborn
IUGR= Intrauterine growth restriction
Pregnancy rate= number of pregnancies per woman
Preg-induced HTN = pregnancy-induced hypertension
Gestational DM= gestational diabetes
APL ab= antiphospholipid antibodies
*
Sum of pregnancy-induced hypertension and toxemia
N= number of publications.