Table 1.
Clinical and laboratory abnormalities in myeloma1
| Clinical/laboratory features | Proportion of patients with abnormality (%) |
|---|---|
| Anemia <12 g/100 ml | 72 |
| Bone lesions (lytic lesions, pathologic fractures or severe osteopenia) | 80 |
| Renal failure (serum creatinine ≥2 mg/100 ml) | 19 |
| Hypercalcemia (≥11 mg/100 ml) | 13 |
| Monoclonal protein on serum protein electrophoresis | 82 |
| Monoclonal protein on serum protein immunofixation | 93 |
| Monoclonal protein on serum plus urine protein immunofixation (or serum immunofixation plus serum free light chain assay) | 97 |
| Type of M protein | |
| IgG | 52 |
| IgA | 21 |
| Light chain only | 16 |
| Increased ≥10% clonal bone marrow plasma cells | 96 |