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Correlations between cytokine production and histologic disease severity in colons of Gi2-/- 129 mice. Spearman's correlation coefficient is indicated, ρ, with significant correlations indicated by ** (P<0.01) and * (P<0.05) Degree of inflammation is positively correlated with increased levels of TNF-α, IL-6, IL-17, IL-12 p40 and IFN-γ. Note that expression of KC is not related to inflammation in these mice.
