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Immunohistochemical staining of colon from 129SvEv mice for CD11c. Gαi2-deficient mice have increased CD11c staining in the lamina propria as well as the absence of well-formed lymphoid follicles compared to WT mice. Note the random distribution of CD11c-staining cells in Gαi2-/- mice compared with the orderly localized subepithelial dome distribution in WT mucosa. Magnification 40x (top); 100x (bottom).
