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CD11b and CD11c immunofluorescence microscopy of cecum of 129SvEv mice. There is increased CD11c staining (green) as well as CD11b (red) in the lamina propria of Gαi2-/- mice compared to WT counterparts. Double-staining cells (yellow) are seen only in inflamed tissue from Gαi2-/- mice and not WT 129, representing CD11c+b+ (double-positive) cells, likely DCs.
