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TNF-α and IL-6 suppression by exogenous IL-10. BMDCs from 129 mice were stimulated by CpG or CpG with exogenous IL-10 (5 ng/ml) and assayed for IL-6 and TNF-α. Expression of inflammatory cytokines in both WT and Gαi2-deficient (K/O) mice were decreased in the presence of exogenous IL-10.
