Table 1.
Group | Age (m) | N | Histologic Score Median (Interquartile range) |
---|---|---|---|
WT B6 | 4-6 | 3 | 0 (0-0.5) |
Gαi2 B6 | 4-6 | 3 | 0 (0-0.5)* |
WT B6 | 9-10 | 2 | 0.5 (0-1) |
Gαi2 B6 | 9-10 | 2 | 2 (1-3) |
WT129 | 4-6 | 6 | 0 (0) |
Gαi2 129 | 4-6 | 6 | 2 (2-3)* |
Histologic scores were significantly worse in Gαi2 129 mice than B6 counterparts at 4-6 m of age (P=0.024) but not at 9-10 m age (P>0.05).