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. 2009 Jan 6;10:1. doi: 10.1186/1471-2296-10-1

Table 2.

Frequency or means (standard deviations) of baseline (1989) characteristics among non-users and new users of benzodiazepines among Quebec elderly.

Variable Frequency or Mean (s.d.) Odds Ratios and 95% Confidence Interval1

Non-Users n = 174,444 New Users n = 78,367
Patients Demographics
Age (in years) 73.6 (6.1) 73.0 (5.7) 0.90 (0.89–0.91)2
Women 50.1% 55.7% 1.20 (1.18–1.22)
Measures of Health Care Use
Number of Prescribing Physicians 1.8 (1.5) 2.1 (1.6) 1.12 (1.11–1.13)
Number of Acute-Care Hospital Discharges 0.2 (0.6) 0.2 (0.5) 0.93 (0.91–0.95)
Charlson Co-morbidity Index 0.5 (1.2) 0.5 (1.2) 0.98 (0.98–0.99)
Diagnosis for impairments or disabilities associated with an increase risk for falls:
Previous Injury from a Fall 4.6% 4.6% 0.93 (0.89–0.97)
Visual Impairment 21.6% 22.7% 0.98 (0.96–1.01)
Arthritis 14.2% 17.2% 1.11 (1.09–1.14)
Stroke 3.0% 2.7% 0.91 (0.86–0.96)
Depression 2.3% 3.6% 1.42 (1.35–1.49)
Neurological Disorders 2.8% 2.9% 0.95 (0.91–1.01)
Seizure Disorders 1.8% 1.8% 0.91 (0.85–0.97)
Osteoporosis 0.5% 0.5% 1.00 (0.88–1.12)
Miscellaneous Impairments 4.1% 4.6% 1.01 (0.97–1.06)
Alcohol Abuse/Dependence 0.3% 0.3% 1.24 (1.05–1.46)
Drug Abuse/Dependence 0.2% 0.2% 1.18 (0.99–1.42)
Non-benzodiazepine medication protective of fractures:
Thiazide Diuretics & Estrogens 20.6% 23.3% 1.05 (1.03–1.08)
Non-benzodiazepine medication associated with an increase risk of falls:
Anti-Depressants 2.1% 4.4% 1.85 (1.75–1.95)
Anti-Psychotics 1.3% 1.7% 1.11 (1.03–1.19)
Sedatives 2.6% 4.2% 1.37 (1.31–1.44)
Other Psychotropics 0.1% 0.2% 1.39 (1.14–1.71)
Non-benzodiazepine medications known to alter motor stability:
Cardiac Drugs 26.1% 30.2% 1.04 (1.02–1.06)
Anti-Hypertensives 12.0% 13.9% 1.06 (1.03–1.09)
Vasodilators 12.8% 16.5% 1.21 (1.18–1.24)
Opioid Agonists 0.6% 0.8% 1.11 (1.01–1.23)
Mixed Partial Opioid Agonists/Antagonists 10.8% 12.1% 1.02 (0.99–1.05)

1 Adjusted for all other potential predictors in multivariable logistic regression model.

2 Odds ratio per 5 year increase in age.