Table 1.
Selected characteristics of participating cases and controls [n (%)] by leukemia histological type: NCCLS.
| ALL
|
AML
|
|||
|---|---|---|---|---|
| Characteristic | Cases | Controls | Cases | Controls |
| Total | 550 | 737 | 100 | 125 |
| Sex | ||||
| Male | 311 (56.5) | 415 (56.3) | 55 (55.0) | 68 (54.4) |
| Female | 239 (43.5) | 322 (43.7) | 45 (45.0) | 57 (45.6) |
| Age at reference datea (years) | ||||
| 0.0–1.9 | 62 (11.3) | 80 (10.9) | 30 (30.0) | 37 (29.6) |
| 2.0–5.9 | 313 (56.9) | 425 (57.7) | 20 (20.0) | 28 (22.4) |
| 6.0–14.9 | 175 (31.8) | 232 (31.5) | 50 (50.0) | 60 (48.0) |
| Median (interquartile range) | 4.5 (2.8–7.2) | 4.4 (2.8–7.0) | 6.1 (1.7–10.7) | 5.8 (1.8–9.5) |
| Phase of the study | ||||
| Phase 1b | 156 (28.4) | 156 (21.2) | 38 (38.0) | 38 (30.4) |
| Phase 2c | 394 (71.6) | 581 (78.8) | 62 (62.0) | 87 (69.6) |
| Ethnicity | ||||
| Hispanic | 247 (44.9) | 320 (43.4) | 39 (39.0) | 49 (39.2) |
| Non-Hispanic white | 221 (40.2) | 303 (41.1) | 40 (40.0) | 55 (44.0) |
| Non-Hispanic other | 82 (14.9) | 114 (15.5) | 21 (21.0) | 21 (16.8) |
| Household income (US$ 1,000/year) | ||||
| < 15 | 87 (15.8) | 76 (10.3) | 21 (21.0) | 11 (8.8) |
| 15–29 | 98 (17.8) | 105 (14.2) | 17 (17.0) | 17 (13.6) |
| 30–44 | 84 (15.3) | 95 (12.9) | 16 (16.0) | 15 (12.0) |
| 45–59 | 89 (16.2) | 100 (13.6) | 10 (10.0) | 20 (16.0) |
| 60–74 | 48 (8.7) | 80 (10.9) | 12 (12.0) | 14 (11.2) |
| ≥ 75 | 144 (26.2) | 281 (38.1) | 24 (24.0) | 48 (38.4) |
| Father’s education level | ||||
| None or elementary school | 56 (10.2) | 79 (10.7) | 11 (11.0) | 12 (9.6) |
| High school or similar | 196 (35.6) | 224 (30.4) | 36 (36.0) | 43 (34.4) |
| Some college or similar | 116 (21.1) | 188 (25.5) | 18 (18.0) | 29 (23.2) |
| Bachelors degree or higher | 163 (29.6) | 216 (29.3) | 32 (32.0) | 40 (32.0) |
| Missing | 19 (3.5) | 30 (4.1) | 3 (3.0) | 1 (0.8) |
| Mother’s education level | ||||
| None or elementary school | 69 (12.5) | 58 (7.9) | 13 (13.0) | 11 (8.8) |
| High school or similar | 168 (30.5) | 210 (28.5) | 30 (30.0) | 35 (28.0) |
| Some college or similar | 159 (28.9) | 239 (32.4) | 24 (24.0) | 33 (26.4) |
| Bachelors degree or higher | 154 (28.0) | 229 (31.1) | 33 (33.0) | 46 (36.8) |
| Missing | 0 (0.0) | 1 (0.1) | 0 (0.0) | 0 (0.0) |
| Father’s age at child’s birth (years) | ||||
| Median (interquartile range) | 31.0 (25.7–35.6) | 31.2 (26.5–35.8) | 29.6 (25.5–34.9) | 32.4 (26.0–35.5) |
| Mean ± SD | 30.9 ± 7.1 | 31.4 ± 7.0 | 30.8 ± 7.2 | 31.5 ± 6.6 |
| Mother’s age at child’s birth (years) | ||||
| Median (interquartile range) | 28.8 (23.5–32.9) | 28.8 (24.2–33.5) | 27.7 (23.2–31.6) | 29.6 (25.5–33.2) |
| Mean ± SD | 28.4 ± 6.1 | 29.0 ± 6.1 | 27.9 ± 6.4 | 29.4 ± 6.0 |
a
Reference date was defined as the date of diagnosis for cases and corresponding date for matched controls.
b
August 1995 through November 1999, covering 17 counties: Alameda, Contra Costa, Marin, Merced, Monterey, Napa, Sacramento, San Benito, San Francisco, San Joaquin, San Mateo, Santa Clara, Santa Cruz, Solano, Sonoma, Stanislaus, and Yolo.
c
December 1999 through December 2005, covering 35 counties: 17 counties from phase 1, plus Amador, Butte, Calaveras, Colusa, El Dorado, Fresno, Glenn, Kern, Kings, Madera, Mariposa, Nevada, Placer, San Luis Obispo, Sutter, Tulare, Tuolumne, and Yuba.