Table 2. Optimal cut-off, area under the ROC-curve (Area), and diagnostic sensitivity and specificity of statistically significant biochemical markers.

Marker	Area	Cut-off	Sensitivity	Specificity
MCP-1	0.886	243.00	0.85	0.92
VEGF	0.805	7.80	0.78	0.85
EGF	0.798	68.00	0.69	1.00
Prolactin	0.699	380.00	0.60	0.79
TSH	0.624	1.80	0.58	0.69
Testosterone	0.618	3.73	0.63	0.65