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Comparison of pfmdr1 copy number and clinical failure outcome. Artesunate-mefloquine: ACPR (N = 103, copy number ≥ 2 = 20); LTF (N = 9, copy number ≥ 2 = 7); * p < 0.001. Artemether-lumefantrine: ACPR (N = 76, copy number ≥ 2 = 8); LTF (N = 20, copy number ≥ 2 = 4), p = 0.257 (the analysis was tested by Wilcoxon rank-sum (Mann-Whitney) test). The black horizontal lines and number represent geometric mean pfmdr1 copy number.
