Fig. 9.

Insulin and C-peptide production. AAV-transduced hMSCs, untransduced hMSCs, and HIT-T15 cells are shown. Insulin production of cells at 1 week (a), 2 weeks (c), and 3 weeks (e) post-transduction and C-peptide production at 1 week (b), 2 weeks (d), and 3 weeks (f) post-transduction were tested. Insulin secretion from 1-3 week(s) post-transduction maintained a similar level or decreased slightly (c). C-peptide secretion from 1 week to 3 weeks post-transduction (d). Data were tested using ANOVA (a~g, p < 0.005).