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Western blot analysis of 15-PGDH in gastric carcinomas and methylation specific PCR with methylated 15-PGDH primer sets (M) and unmethylated 15-PGDH primer sets (U) in gastric carcinomas. The promoter methylation of 15-PGDH was not observed in 2 gastric carcinomas (T1 and T3) with negligible expression of the enzyme. 15-PGDH, 15-hydroxyprostaglandin dehydrogenase.
