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Predicted vs. Observed Aprepitant Exposure for a 2-mg/kg Suspension Administration in Dogs
| Particle size (μm) | Predicted AUC (μg h/mL) | Observed AUC (μg h/mL) |
|---|---|---|
| 5.49 | 5.85 | 5.88 ± 1.86 |
| 1.85 | 6.94 | 7.54 ± 1.86 |
| 0.48 | 7.22 | 10.5 ± 2.70 |
| 0.12 | 7.26 | 25.3 ± 3.29 |
Predictions were made across four different particle sizes
