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. 2008 Oct 25;466(12):2981–2994. doi: 10.1007/s11999-008-0556-1

Table 6.

Patients with refractures after initial healing

Patient number Site of refracture Diagnosis Treatment of fracture Time between index operation and refracture (years) Classifications – Boyd [4], El-Rosasy-Paley et al. [14] Age at refracture (years) Fibular PA
1 Through different lesion OFD Frame without grafting 3.7 III, II 10.4 Yes
2 Original PA site Idiopathic Casting + zoledronic acid therapy + fibular transport and then regrafting + tibiofibular synostosis with two screws + BMP-2 and LCP; after two treatments of intravenously administered bisphosphonate, tibia healed but fibula not completely consolidated 1.3 V, I 8 Yes
3 Original PA site NF Casting tried for 3 months (no healing noticed); after zoledronic acid, healing achieved 1.5 II, I 9.4 No
5 Original PA site NF Regrafting + external fixation + proximal lengthening 1.0 II, I 7 Yes
7 Original PA site NF First fracture: FractureFrame + rod exchange without regrafting from titanium nail to FDNSecond fracture: Frame reapplication, regrafting, and rod exchange First refracture, 1.1Second refracture, 6.4 II, I First refracture, 2.3Second refracture, 6.7 Yes
8 Original PA site NF Frame reapplication without grafting and then Rush rod subtalar joint 1.3 II, I 2.8 Yes
10 Original PA site OFD Casting + zoledronic acid, healing achieved 5.8 III, I 7.9 No
11 Original PA site NF First fracture: Healed after 3 months of castingSecond fracture: Frame without grafting and rod insertion at time of frame removal First refracture, 2.8Second refracture, 3.1 II, I First refracture, 5Second refracture, 5.3 Yes

BMP = bone morphogenetic protein; FDN = Fassier-Duval telescopic IM nail; LCP = locking compression plate; NF = neurofibromatosis; OFD = osteofibrous dysplasia; PA = pseudarthrosis.