Table II.

Regression Coefficients and Rate Constants for Diclofenac Release from Coated Pellets

Formulation code	Zero order		First order		Higuchi		Korsmeyer
	k 0	r 2	k 1	r 2	k H	r 2	n	r 2
F1	2.38	0.83	0.02	0.76	14.51	0.72	0.46	0.71
F2	2.74	0.89	0.02	0.8	16.81	0.79	1.11	0.89
F3	1.6	0.89	0.01	0.84	9.81	0.78	1.76	0.93
F4	3.15	0.87	0.03	0.78	19.26	0.76	0.60	0.74
F5	3.73	0.89	0.05	0.67	22.94	0.79	0.65	0.77

F1 coated pellets without plasticizer, F2 coated pellets with 10% TEC, F3 coated pellets with 15% TEC, F4 coated pellets with 10% PEG 6000, F5 coated pellets with 15% PEG 6000, k ₀ zero order rate constant, k ₁ first order rate constant, k _H Higuchi rate constant, n diffusion coefficient, r ² regression coefficient