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. 2008 Dec 31;9(4):1262–1269. doi: 10.1208/s12249-008-9171-4

Table II.

Solubility Study of LS (Mean ± Standard Deviation) from Physical Mixture and Solid Dispersions in Comparison with Pure LS

Product Solubility (μg/ml)
LS 1.28 ± 0.061
PM 3.078 ± 0.112
KW 3.202 ± 0.160
KE 3.399 ± 0.179
SW 3.452 ± 0.204
SP 3.613 ± 0.200
SE 3.717 ± 0.161

n = 3

LS lovastatin, PM physical mixture of lovastatin & modified locust bean gum, KW SDs by kneading method using water, KE SDs by kneading method using ethanol, SW SDs by solvent wetting method SP SDs by spray drying method, SE SDs by solvent evaporation method