Table I.
Formulation code | PLGA | Size distribution (μm) | Span | MP content (%, w/w) | E.E. (%) | ||
---|---|---|---|---|---|---|---|
d 10 a | d 50 b | d 90 c | |||||
MS 4555 2A | DL 4555 2A | 7.8 | 25.1 | 68.7 | 2.4 | 17.2 ± 2.1 | 57.4 ± 7.0 |
MS 2A | DL 5050 2A | 10.4 | 22.5 | 49 | 1.7 | 16.7 ± 2.5 | 55.8 ± 8.2 |
MS 3A | DL 5050 3A | 5.3 | 15.6 | 45.6 | 2.6 | 17.7 ± 1.2 | 58.9 ± 4.1 |
MS 2M | DL 5050 2M | 7 | 18.2 | 46.5 | 2.2 | 17.3 ± 2.0 | 57.8 ± 6.7 |
aTen percent of particles were smaller than that number
bFifty percent of particles were smaller than that number
cNinety percent of particles were smaller than that number