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. 2008 Nov 14;9(4):1136–1142. doi: 10.1208/s12249-008-9158-1

Table I.

Particle Size Distribution and MP Loading of PLGA Microspheres

Formulation code PLGA Size distribution (μm) Span MP content (%, w/w) E.E. (%)
d 10 a d 50 b d 90 c
MS 4555 2A DL 4555 2A 7.8 25.1 68.7 2.4 17.2 ± 2.1 57.4 ± 7.0
MS 2A DL 5050 2A 10.4 22.5 49 1.7 16.7 ± 2.5 55.8 ± 8.2
MS 3A DL 5050 3A 5.3 15.6 45.6 2.6 17.7 ± 1.2 58.9 ± 4.1
MS 2M DL 5050 2M 7 18.2 46.5 2.2 17.3 ± 2.0 57.8 ± 6.7

aTen percent of particles were smaller than that number

bFifty percent of particles were smaller than that number

cNinety percent of particles were smaller than that number