Table 1.
Stable (1-2) and Photolytically Sensitive (4 – 11) Src Inhibitors.
| # | Peptide |
IC50 (nM) |
|---|---|---|
| 1 | Ba-EEEIFGEF-Dap(Hna)-βA3-pYEEIEXa | 35 ± 2 |
| 2 | Ba-EEEIFGEF-Dap(Hna)X + AcpYEEIE-NH2 (3) | 1900 |
| 4 | Ba-EEEIFGEF-Dap(Hna)-βA-I-βA-pYEEIEX | 115 ± 9 |
| 5 | Ba-EEEIFGEF-Dap(Hna)-βA-II-βA-pYEEIEX | 38 ± 4 |
| 6 | Ba-EEEIFGEF-Dap(Hna)-βA-III-βA-pYEEIEX | 18 ± 5 |
| 7 | Ba-EEEIFGE-II-Dap(Hna)-βA3-pYEEIEX | 220 ± 10 |
| 8 | Ba-EEEI-III-GEF-Dap(Hna)-βA3-pY-III-EIEX | 28000 |
| 9 | Ba-EEEIFGE-III-Dap(Hna)-βA3-pY-III-EIEX | 7500 |
| 10 | Ba-EEEIFGEF-Dap(Hna)-βA-III-βA-pY-III-EIEX | 1600 |
| 11 | Ba-EEEIFGEF-Dap(Hna)C-III-βA-pYEEIE-NH2 | 56 ± 4 |
a
