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HOG-LDL induces apoptosis in HRCP. After 12 h, 200 mg/l highly oxidized-glycated low density lipoprotein (HOG-LDL) caused a 2–3 fold increase in apoptosis (measured by Annexin V FITC and propidium iodide) compared to serum-free medium (SFM) and native-low density lipoprotein (N-LDL). A combination of N-LDL and HOG-LDL did not inhibit HOG-LDL-induced apoptosis. Bars represent mean±SD of three separate experiments. The asterisk indicates p<0.05 compared to SFM.
