Nitrendipine prevented the decrease in GABA currents after 4h hypoxia. (A) Peak currents elicited by increasing GABA concentrations in control cells (filled squares) and immediately (0 h, open circles), 24 h (open triangles) and 48 h (open diamonds) after 4 h hypoxia in the presence of nitrendipine (NT, 3 μM). Each symbol represents means of peak currents evoked at that GABA concentration. (B) Maximal GABA currents normalized to cell capacitance for control cells and at each recovery time point after 4 h hypoxia, with or without NT. There was no significant difference in current density between control and 4 h hypoxia-treated neurons in the presence of NT during hypoxia (ρ>0.05, one way ANOVA).