Table 3. Maximal GABAAR Currents Normalized to Membrane Capacitance after Hypoxia and Recovery.
Maximal GABA-evoked currents normalized to membrane capacitance at specified recovery times after 3 different hypoxic durations.
| Hypoxia | Control (pA/pF) | 0 h Recovery (pA/pF)) | 24 h Recovery (pA/pF)) | 48 h Recovery (pA/pF) |
|---|---|---|---|---|
| Duration | Mean ± SEM (n) | Mean ± SEM (n) | Mean ± SEM (n) | Mean ± SEM (n) |
| 2 h | 247.2 ± 17.3 (9) | 199.5 ± 17.6 (8) | 198.4 ± 12.7 (9) | 296.9 ± 26.2 (9) |
| 4 h | 211.5 ± 22.5 (10) | 132.7 ± 15.6 (9)* | 180.0 ± 26.1 (7) | 121.2 ± 10.7 (10)** |
| 8 h | 214.0 ± 22.7 (10) | 148.4 ± 31.6 (6) | 177.3 ± 18.0 (8) | 187.4 ± 18.8 (9) |
| 4 h + NT | 341.1 ± 27.4 (11)** | 357.5 ± 36.0 (8)*** | 309.5 ± 48.7 (8)* | 337.8 ± 26.7 (9)*** |
*
p<0.05,
**
p<0.01 relative to control, t test with Bonferroni correction. after one way ANOVA.