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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Neuropharmacology. 2008 Jul 12;56(1):198–207. doi: 10.1016/j.neuropharm.2008.07.004

Table 5. EC50 (or IC50) of Allosteric Agent Effects on GABA Currents After 4 h Hypoxia.

Control 0 h Recovery EC50 24 h Recovery EC50 48 h Recovery EC50
EC50 (μM) (95% CI, n) EC50 (μM) (95% CI, n) EC50 (μM) (95% CI, n) EC50 (μM) (95% CI, n)
Diazepam 0.12 (0.05–0.30, 10) 0.06 (0.04–0.09, 8) 0.08 (0.04–0.14, 8) 0.08 (0.05–0.13, 8)
Zolpidem 0.10 (0.06–0.17, 10) 0.12 (0.05–0.30, 8) 0.38 (0.13–1.14, 6) 0.16 (0.11–0.24, 8)
Pentobarbital 59.7 (27.5–130, 8) 37.3 (10.3–134, 2) 54.7 (18.3–163, 6) 57.1 (35.9–90.9, 7)
Zinc 42.6 (29.5–61.6, 6) 27.3 (13.9–53.7, 5) 75.3 (48.3–117, 6) 30.0 (20.7–43.5, 6)