Figure 5. Prolonged Synaptic Currents in OHCs.

(A) Representative traces of IPSCs evoked by 40 mM K⁺ in OHCs of P10–P11 Chrna9^wt/wt mice at a V _hold of −90 mV. The insets show synaptic currents on an expanded time scale.

(B) Same as in (A) but for Chrna9^{L9′T/L9′T} mice.

(C) Superimposed representative traces of nAChR+SK2 synaptic currents from a Chrna9^wt/wt; (39 events) and a Chrna9^{L9′T/L9′T} (77 events) mice. The representative traces shown are the average of the different events in one cell (number of cells per experiment indicated in Table 2). Vh, V _hold; WT, wild type.

(D) Representative responses of OHCs to 1 mM ACh at a V_hold of −90 mV and −40 mV.