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. 2009 Jan 20;7(1):e1000018. doi: 10.1371/journal.pbio.1000018

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© 2009 Taranda et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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By 1 h postinjection, thresholds in mutant mice recovered to the mean value from wild types (23 dB SPL at 22.6 kHz: Figure 5B). Strychnine produced no systematic effects on wild-type (WT) thresholds. Here, DPOAE thresholds for f₂ = 22.6 kHz were repeatedly measured before and after a 30-mg/kg i.p. strychnine injection in a Chrna9^wt/wt and a Chrna9^{L9′T/L9′T}. The effect of strychnine was concentration-dependent as shown in Figure S3.