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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2008 Nov;17(11):3043–3050. doi: 10.1158/1055-9965.EPI-08-0645

Table 3.

Intraclass correlation coefficients for the reliability of the three tissue core samples

All tumorsa Invasive Borderline ≤ 10 yearsb > 10 years
Antigen ICCc ρd ICC ρ ICC ρ ICC ρ ICC ρ
Ki-67 0.94 0.93 0.93 0.92 0.96 1.00 0.89 0.88 0.95 0.94
PR 0.95 0.93 0.95 0.93 0.92 0.93 0.95 0.93 0.95 0.93
p53 0.97 0.96 0.97 0.96 0.80 0.75 0.98 0.97 0.96 0.95
ER- α 0.91 0.91 0.92 0.92 0.79 0.76 0.89 0.92 0.91 0.90
WT-1 0.98 0.98 0.99 0.99 0.85 0.93 >0.99 0.99 0.96 0.96
CK7 0.94 0.96 0.94 0.95 0.92 0.96 0.95 0.96 0.93 0.95
CK20 0.97 0.87 0.97 0.87 n/ae n/a n/a n/a 0.97 0.87
a

Range for the number of observations used (with non-missing data): all tumors 413-486; invasive 376-400; borderline 45-52; ≤ 10 years old 154-181; >10 years old 178-303.

b

Age was dichotomized into ≤ 10 and >10 years old at of the time of staining.

c

ICC were calculated using the using the log transformed values for each stain.

d

ρ is the mean Spearman correlation of three cores from each tumor sample.

e

Too many missing observations (n = 47) to perform the calculation.