Table 5.
Concordance and percent agreement between two pathologists
| ER-α | Ki-67 | |
|---|---|---|
| Between Individual Cores | n = 288 | n = 267 |
| Cohen's κ (95% CI) | 0.79 (0.74-0.83) | 0.52 (0.45-0.59) |
| Percent agreementa | 192 (73%) | 141 (53%) |
| Between Maximum Stain of Three Cores | n = 101 | n = 96 |
| Cohen's κ (95% CI) | 0.73 (0.65-0.82) | 0.55 (0.44-0.66) |
| Percent agreement | 63 (66%) | 50 (52%) |
| Between Dichotomized Valueb | n = 96 | n = 96 |
| κ (95% CI) | 0.65 (0.50-0.81) | 0.67 (0.53-0.82) |
| Percent agreement | 81 (84%) | 81 (84%) |
a
Number of cores that were scored the same by the two pathologists.
b
The maximum stain of the three cores was dichotomized (positive if staining in >10% of cells).