Skip to main content
. Author manuscript; available in PMC: 2009 Nov 25.
Published in final edited form as: Vaccine. 2008 Oct 1;26(50):6329–6337. doi: 10.1016/j.vaccine.2008.09.031

Figure 5.

Figure 5

Protective efficacy of single-dose VSV-ssLcrV or VSV-LcrV vaccine in a plague challenge assay. (A) Survival profile of VSV-ssLcrV1 vaccinated mice following lethal plague challenge. Mice were immunized (IM) with VSV-ssLcrV1 at three different doses - 107 pfu (open triangle), 108 pfu (open diamond) or 109 pfu (open square). The control mice received VSV-eGFP1 (open circle). All animals were challenged at 3 months post vaccination with 10LD50 Y. pestis (CO92) and observed for 14 days. (B) Similar to A, except that animals were vaccinated with three different doses of VSV-LcrV1 - 107 pfu (open triangle), 108 pfu (open diamond) or 109 pfu (open square).