Figure 2. CK-18 fragments are increased with the severity of fibrosis on liver biopsy.
Vertical axis is plasma CK-18 levels in U/L and horizontal axis is the grade of fibrosis. The box represents the interquartile range (the 25th and 75th percentiles) from the median (the horizontal line), the bars the 95% confidence interval. CK-18 fragment levels were significantly higher in patients with moderate to severe fibrosis (stage 2–3) compared to those patients with no or mild fibrosis (stage 0–1).