Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 Dec 31;28(53):14329–14340. doi: 10.1523/JNEUROSCI.4833-08.2008

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2008 Society for Neuroscience 0270-6474/08/2814329-12$15.00/0

PMC Copyright notice

Figure 3. — Distribution of the Nav1.6, Kv1.1, and Kv1.2 subunits in the AIS of neocortical PCs. A, B, Double immunofluorescent reactions demonstrate the colocalization of Nav1.6 and Kv1.1 immunolabeling in layer 2/3 PC AISs. B, High-magnification images of a layer 2/3 PC reveal a gradual increase of Nav1.6 and Kv1.1 labeling toward the distal part of the AIS. Immunolabeling for the Kv1.1 subunit begins more distally (arrowheads) compared with that of the Nav1.6 subunit. C, High-magnification images of a layer 5 PC demonstrate a more even Nav1.6 subunit immunolabeling; it appears proximally, close to the axon hillock, whereas the Kv1.1 immunolabeling emerges more distally (arrowheads). D, A double immunofluorescent reaction shows the colocalization of Nav1.6 and Kv1.2 subunits in layer 2/3 PC AISs. E, High-magnification images of a layer 2/3 PC reveal a gradual increase of Nav1.6 and Kv1.2 labeling along the AIS. Immunolabeling for the Kv1.2 subunit begins more distally (arrowheads) compared with that of the Nav1.6 subunit. F, High-magnification images of a layer 5 PC demonstrate a rather uniform distribution of Nav1.6 subunit immunolabeling, whereas the Kv1.2 immunolabeling appears a bit more distally (arrowheads). So, Soma. Scale bars: A, D, 10 μm; B, C, E, F, 5 μm.