TABLE 1.

Pancreatic islet size analysis of wild-type and N171-82Q Huntington's disease mice treated with either saline or Ex-4

	Wild type			N171-82Q Huntington's disease
	Control	Ex-4	P value	Control	Ex-4	P value
Islet area (μm2)	15,101 ± 2,546	12,606 ± 2,652	0.501	2,590 ± 601	13,193 ± 2,496	<0.001*
Major axis (μm)	211.5 ± 19.0	185.3 ± 21.5	0.369	91.6 ± 11.6	203.9 ± 31.9	0.003†
Minor axis (μm)	154.1 ± 13.5	132.7 ± 13.6	0.272	65.8 ± 8.6	126.1 ± 13.1	<0.001*

Data are means ± SEM unless otherwise indicated.

^*P < 0.001;

^†P < 0.01.