TABLE 1.

Intraportal glucose infusion clamp in the presence of postprandial hyperinsulinemia and hyperglycemia: basal and clamp steady-state parameters in the saline- and exenatide-treated groups

	Basal		Clamp steady state
	Saline	Exenatide	Saline	Exenatide
Glucose (mg/dl)	92.6 ± 1.6	89.4 ± 2.1*	150.2 ± 2.8†	157.4 ± 4.3†
Insulin (pmol/l)	41.3 ± 4.5	45.8 ± 4.0	231.5 ± 10.5†	217.9 ± 11.5*†
C-peptide (ng/ml)	0.24 ± 0.06	0.25 ± 0.06	0.06 ± 0.06†	0.05 ± 0.04†
Glucagon (ng/l)	42.5 ± 4.2	50.8 ± 6.4	33.3 ± 3.2	33.5 ± 3.9†
FFAs (mmol/l)	0.58 ± 0.06	0.55 ± 0.11	0.02 ± 0.01†	0.03 ± 0.03†

Data are means ± SE.

^*P < 0.05 significantly different from the saline group.

^†P < 0.05 significantly different from basal in each group.